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上海信裕生物科技有限公司
Seladin 1抗体

Seladin 1抗体

商家询价

产品名称： Seladin 1抗体

英文名称： Seladin 1Antibody

产品编号： XY10471-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 SELADIN 1抗体Applications

In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 3 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse, rat
Images
Prev1NextView more validation data
  • 10471-1-AP;Jurkat cellJurkat cells were subjected to SDS PAGE followed by western blot with 10471-1-AP(DHCR24 antibody) at dilution of 1:800
  • 10471-1-AP;Breast cancerImmunohistochemical of paraffin-embedded human breast cancer using 10471-1-AP(DHCR24 antibody) at dilution of 1:100 (under 25x lens)
Positive WB detected in Jurkat cells, HEK-293 cells, HepG2 cells, MCF7 cells, mouse lung tissue
Positive IHC detected in Human breast cancer tissue, human liver tissue, human lung tissue, human ovary tissue, human placenta tissue, human skin tissue, human spleen tissue, human testis tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
SELADIN 1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Seladin 1 fusion protein ag0756 Full name 24-dehydrocholesterol reductase
Calculated molecular
weight		 60 kDa/516aa Observed molecular 
weight		 60kd
GenBank accession 
number		 BC004375 Gene ID (NCBI) 1718
Gene symbol DHCR24 Synonyms DHCR24, Diminuto/dwarf1 homolog, KIAA0018, Nbla03646, Seladin 1, SELADIN1
BackgroundSELADIN 1抗体

DHCR24(3-beta-hydroxysterol delta-24-reductase), a member of the flavin adenine dinucleotide (FAD)-dependent oxidoreductases, catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis.The dhcr24 expression was shown to be downregulated in brain areas affected by Alzheimer’s disease and endogenous DHCR24/seladin-1 levels are highly up-regulated upon acute oxidative stress while expression declines to very low levels upon chronic exposure(PMID:17984220).SELADIN 1抗体

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