货号：70R-1584

名称：Renin antibody

规格：100ug

产品描述：

别名：Polyclonal Renin antibody, Anti-Renin antibody, REN antibody, FLJ10761 antibody

特异性：Renin antibody was raised against the C terminal of REN

交叉反应: Human,Mouse,Rat

应用：WB

免疫原：Renin antibody was raised using the C terminal of REN corresponding to a region with amino acids YSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALA

试剂信息：Renin Blocking Peptide, catalog no. 33R-10250, is also available for use as a blocking control in assays to test for specificity of this Renin antibody

来源：Rabbit

纯化方法：Total IgG Protein A purified

分子量大小：45 kDa (MW of target protein)

形成和缓冲液：Supplied as liquid, in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

浓度：1 mg/ml

使用浓度：WB: 2.5 ug/ml

保存：Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

生物学意义：Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in this gene have been shown to cause familial hyperproreninemia.

关于Fitzgerald

Fitzgerald公司始于1989年，是全球著名的抗体、蛋白及其他科研试剂生产商。可提供超过45,000种产品，可为科研机构、诊断机构和制药公司提供包括单抗、多抗、天然和重组蛋白、ELISA试剂盒等多种试剂。

Fitzgerald的特色产品有PSA蛋白； CA 125, CA 15-3, CA 19-9 和 CA 50 抗体, GAPDH 抗体；Influenza单抗；心肌标志物如CKMM蛋白和Apo抗体；激素和类固醇多抗如**(testosterone)抗体, 孕酮(progesterone)抗体,和甲状腺素(thyroxine)抗体。

产品涉及领域

特色产品简介---------

激素相关抗体和蛋白

激素及其受体在调节基因表达中发挥着重要的作用，Fitzgerald可提供超过800种激素抗体和纯化的激素用于研究激素及其受体的功能，包括类固醇激素如糖皮质激素、雌激素、雄激素；小分子肽类激素TRH和血管加压素；蛋白激素如胰岛素、生长激素；糖蛋白激素如LH,TSH和FSH。

GAPDH抗体和蛋白

GAPDH是一种管家基因（house keeping gene），在维持多种细胞的功能中发挥着重要作用，由于高水平普遍表达，GAPDH抗体主要用于western blot实验中作为内参抗体。Fitzgerald可提供多种GAPDH单抗、多抗、蛋白、封闭肽。

Western Blot analysis using GAPDH antibody (10R-1931)

Western Blot showing GAPDH antibody used against Hela (1), A549 (2), A431 (3), MCF-7 (4), K562 (5), Jurkat (6), HL60 (7), SKN-SH (8) and SKBR-3 (9) cell lysate.

肿瘤相关抗体和蛋白

Fitzgerald提供乳腺癌、前列腺癌、肺癌、卵巢癌、睾丸癌、胃癌、膀胱癌、肾癌、脑癌等多种肿瘤相关的抗体和到蛋白，如HE4, BRCA, MUC1, CA 15-3, CA 19-9,CA 27-29, CA 125, ERBB2, CEACAM, Neu, c-myc, Survivin, p53,IGF, CEA, AFP, PSA, PAP等多种指标。

PSA antibody, Cat. No. 10R-2123 staining of paraffin-embedded human prostate tissues

免疫学相关抗体和蛋白

Fitzgerald免疫学产品线有超过6000种产品，包括天然和重组蛋白；针对多种免疫系统指标的单抗和多抗，涵盖了健康和疾病状态，也包括免疫失调如自身免疫性疾病、过敏和免疫缺陷。